PathoIntern – AI-assisted blood smear triage
Phase I MVP · Non-Diagnostic

No critical blood smear
should wait for review.

To help pathologists prioritize blood smear slides through safe, non-diagnostic AI triage — so expertise is applied where it matters most.

How PathoIntern Works

A four-step pipeline that assists — never replaces — the pathologist's judgment.

01

Upload Patch

Lab technologist uploads a digitized blood smear patch image (PNG/JPG).

02

Generate Embedding

CTransPath encodes the patch into a 768-dimensional morphological feature vector.

03

Score & Prioritize

k-NN anomaly detection assigns a 0–100 criticality score and Urgent/High/Elevated/Routine tier.

04

Pathologist Reviews

Pathologist reviews the prioritized worklist, views similar cases, and submits a verdict.

Four-Tier Triage Classification

Scores represent pattern similarity to reviewed cases — not diagnostic probability.

Final interpretation always by licensed pathologist

80–100
Urgent
Immediate review required. Highest anomaly signal.
60–79
High
Priority review. Significant departure from baseline.
40–59
Elevated
Moderate signal. Review before end of shift.
0–39
Routine
Standard queue. Pattern close to normal baseline.

Scientific Foundation

Four peer-reviewed publications support the problem statement and technical approach.

1

Khatab et al. (2024)

Critical Reviews in Clinical Laboratory Sciences

Pathologist workloads rising 5–10% annually. Burnout causes diagnostic errors. No AI triage tools currently exist for blood smear review.

2

Baltruschat et al. (2021)

European Radiology

AI-driven worklist reordering cut critical-case turnaround by 56% — without the AI making any diagnoses. Triage, not diagnosis.

3

Dippel et al. (2024)

NEJM AI

CTransPath + anomaly detection achieved 95% AUROC for histopathological triage — the exact approach PathoIntern implements.

4

Chen et al. (2024)

Nature Medicine

UNI foundation model embeddings generalize across 34 pathology tasks, validating embedding-based similarity search for Phase II.

Built for Pathologists. Controlled by Pathologists.

PathoIntern acts as a digital intern — it performs first-pass analysis and flags anomalies. Every decision, every override, every verdict is fully audited. The pathologist always has the final word.